If you change the Placement transform in a 'VRC Avatar Pedestal component', the pedestal will stop working. Interacting with it will only give the error, "EXCEPTION: Object reference not set to an instance of an object." and the avatar image will stop displaying properly.

Reproduction: Take the AvatarPedestal prefab included in the SDK, drag it into the scene, and change the Placement transform to something else. Build & Test and click on the pedestal. Your avatar will not change and the log will give an error.

Attached is a screenshot of the setup in Unity. Note that only the Placement transform has been changed and nothing else.

Test world: wrld_7c6d630d-a7a2-4050-97e2-7fec4519e5a1