With a SteamVR controller that reports a full skeleton, VRC defaults to hand tracking input behavior. In the 1530 Beta with the new Quick Menu openers, the controller's binding for opening the menu acts as if it were completely disabled.
VRC should still respect the SteamVR controller bindings even though there is hand tracking input. The current behavior in the beta is problematic when using gloves with physical button inputs, for example.
Ideally, hand gesture controls would be disabled via in-game setting or start-up parameter, at least on SteamVR PC, where more exotic hand tracking / input solutions exist.
Possibly related to this comment in the VRC open-beta-discussion channel: https://discord.com/channels/189511567539306508/449386885299830794/1299084757375651850