Now that we're on Unity 2022, it supports the Unity UI Toolkit which is a framework and toolkit to create UI documents that can run in the editor and in-game.
The benefit mostly here is that people can utilize the UI builder for the toolkit to generate UXML documents and programmers can craft UXML documents as well.
In basic terms, people can build a UI that can be displayed in-game without having to craft hundreds of game objects to make a functional UI.