When downloading avatars in the Unity 2022 beta the game can freeze for up to 5 seconds.
The effect seems to be worse in some worlds, though that may just be overall cpu load or something as I can't see anything obviously in common. It does not happen when loading a cached avatar, only when downloading. Even just clicking on an avatar in the menu to preview it causes the lag spike.
The effect was especially noticeable in the following world: https://vrchat.com/home/launch?worldId=wrld_5ade8cc2-83ba-46ba-bd44-5c9e363981f4